Research & Development

Science at Our Core

UAB invests over 22% of annual revenues in R&D. Our integrated discovery-to-development platform spans early target identification through to global regulatory submissions — with a single goal: delivering transformative medicines to patients faster.

Therapeutic Focus

Our Research Areas

Concentrated expertise in six disease areas where the unmet medical need is greatest and the science is most compelling.

Oncology

Targeted therapies and immuno-oncology approaches for solid tumours and haematological malignancies, with a focus on resistance mechanisms and precision medicine.

Neurology

Disease-modifying therapies for neurodegenerative conditions including Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

Cardiovascular

Novel lipid-lowering agents, anti-thrombotic therapies, and heart failure treatments addressing residual cardiovascular risk in high-risk patients.

Immunology

Selective immunomodulatory approaches for autoimmune and inflammatory conditions including atopic dermatitis, psoriatic arthritis, and IBD.

Rare Diseases

Enzyme replacement therapies and gene therapy approaches for ultra-rare lysosomal storage disorders with significant unmet medical need.

Infectious Disease

Antifungal and antiviral agents targeting resistant pathogens of significant public health concern, with a focus on MENA-prevalent infections.

Capabilities

Our Drug Discovery & Development Platform

End-to-end internal capabilities from molecule to medicine.

Target Identification & Validation

AI-powered genomic and proteomic analysis to identify disease-relevant targets with strong genetic validation.

Medicinal Chemistry

Multi-disciplinary teams designing and optimising small molecule drug candidates with superior selectivity and drug-like properties.

Structural Biology

Cryo-EM and X-ray crystallography facilities enabling structure-based drug design for challenging target classes.

Translational Sciences

Biomarker development and patient stratification strategies to maximise proof-of-concept success rates in early clinical trials.

Clinical Development

Phase I–III clinical trial design and execution across 23 countries with specialist CRO partnerships and in-house biometrics.

Regulatory Sciences

Integrated regulatory strategy from early development through to global submissions and post-marketing lifecycle management.

Interested in Research Collaboration?

UAB actively pursues academic partnerships, CRO collaborations, and co-development agreements. Contact our BD team to explore opportunities.